Publications

 

2011

1. Katharina Lückerath, Vladimir Kirkin, Inga Maria Melzer, Frederic Thalheimer, Dagmar Siele, Wiebke Milani, Thure Adler, Antonio Aguilar-Pimentel, Marion Horsch, Geert Michel, Johannes Beckers, Dirk H. Busch, Markus Ollert, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Frank J. T. Staal, Krishnaraj Rajalingam, Lothar J. Strobl, Ursula Zimber-Strobl and Martin Zörnig (2011). Immune modulation by Fas Ligand reverseSignaling: Lymphocyte proliferation is attenuated by the intracellular Fas Ligand domain. Blood 117(2): 519-29.
   
   

2. Krishnaraj Rajalingam, F. Gisou van der Goot (2011). When cells and microbes meet in Krakow. EMBO reports 12(3): 188-90.
   
   

3. Krishnaraj Rajalingam, Ivan Dikic (2011) Healthy aging through regulated proteostasis EMBO J 30(15):2983-5.
   
   

4. Gergely Imre, Sarit Larisch, Krishnaraj Rajalingam (2011) Ripoptosome- a novel IAP-regulated cell death signaling platform (J Mol Cell Biol. Nov 23. [Epub ahead of print]
   
   

5. Tripat Kaur Oberoi* Taner Dogan*, Jennifer C.Hocking, Rolf-Peter Scholz, Juliane Mooz, Carrie L Anderson, Christiaan Karreman, Dagmar Meyer zu Heringdorf, Gudula Schmidt, Mika Ruonala, Kazuhiko Namikawa, Gregory S Harms, Alejandro Carpy, Boris Macek, Reinhard W Koester and Krishnaraj Rajalingam (2011) Inhibitor of Apoptosis proteins regulate the plasticity cell migration by directly targeting Rac1 for degradation EMBOJ- Nov 25. doi: 10.1038/emboj.2011.423. [Epub ahead of print]

 

 

 

 

 

2010

1. Wesley E. Straub, Tobias A. Weber, Birgit Schäfer, Eleonora Candi, Florian Durst, Horng Der Ou, Jan Heering, Krishnaraj Rajalingam, Gerry Melino and Volker Dötsch. (2010) The C-terminus of p63 Contains Multiple Regulatory Elements with Different Functions (Cell death &Disease-in press).

 

2009

1. Vera Kozjak-Pavlovic*, Elke A. Dian*, Michael Meinecke*, Oliver Kepp*, Katharina Ross, Krishnaraj Rajalingam, Anke Harsman, Eva Hauf, Volker Brinkmann, Ines Herrmann, Robert Hurwitz, Dirk Günther, Joachim Rassow, Richard Wagner, Thomas Rudel. (2009) Bacterial porin integrated into mitochondrial inner membrane dissipates membrane potential and sensitizes host cells to apoptosis. PloS Pathogens Oct;5(10):e1000629. Epub 2009 Oct 23.
   
   

2. Philippe C. Morand, Marek Drab, Krishnaraj Rajalingam, Xavier Nassif and Thomas F.Meyer. (2009) Neisseria meningitidis differentially controls host cell motility with PilC1 and PilC2 components of type-4 pili PloS ONE 4(8):e6834.
   
   

3. Oliver Kepp, Kathleen Gottschalk, Yuri Churin, Krishnaraj Rajalingam, Guido Kroemer, Thomas Rudel. (2009) Bim and Bmf dependent apoptosis during Neisseria gonorrhoea infection PloS Pathogens 5(3):e1000348.
   
   
4. Andreas Fischer, Angela Baljuls, Jörg Reinders, Elena Nekhoroshkova, Claudi Sibilski, Renate Metz, Stefan Albert, Krishnaraj Rajalingam, Mirko Hekman, and Ulf R. Rapp (2009) Regulation of RAF Activity by 14-3-3 Proteins –RAF Kinases Associate Functionally with both Homo- and Heterodimeric forms of 14-3-3 Proteins Journal of Biological Chemistry 30;284(5):3183-94.
   
   
5. Krishnaraj Rajalingam and Ivan Dikic (2009). Inhibitors of Apoptosis catch ubiquitin. Biochemical Journal 1;417(1):e1-3.
   
   

 

2008

1. Taner Dogan, Gregory S.Harms, Mirko Hekman, Christiaan Karremann, Tripat kaur Oberoi, Emad S.Alnemri, Ulf R Rapp, Krishnaraj Rajalingam. (2008) X linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility. Nature Cell Biology 10 (12):1447-55.
   
   
2. Krishnaraj Rajalingam*, Manu Sharma*, Christine Wolkewitz, Monique Oswald, Christopher J. Froelich, Thomas Rudel. (2008) Mcl-1 is a key regular of apoptosis resistance in Chlamydia trachomatis infected cells. PloS ONE 3(9):e3102
   
   
3. Anatoly Samoylenko, Nadiya Byts, Krishnaraj Rajalingam, Nico von Ahsen, Ulf R. Rapp, Hannelore Ehrenreich and Anna-Leena Sirén. (2008) Thrombopoietin inhibits nerve growth factor-induced neuronal differentiation and ERK1/2 signalling. Cellular Signalling 20(1):154-62.

 

2007

1. Krishnaraj Rajalingam, Monique Oswald, Kathleen Gottschalk, Thomas Rudel. (2007) Smac is required for effector caspase activation during apoptosis in human cells. Apoptosis 12(8):1503-10.
   
   

2. Krishnaraj Rajalingam, Ralf Schreck, Ulf R Rapp, Stefan Albert. (2007) Ras oncogene and effectors. Biochimica et Biophysica Acta-Molecular Cell Research 1773(8):1177-95.
   
   

3. Oliver kepp§, Krishnaraj Rajalingam§, Sonja Kimmig, and Thomas Rudel. (§Equal contribution) (2007) Bax and Bak are functionally non redundant during Neisseria gonorrhoea and DNA damage- induced apoptosis. EMBO journal 26(3):825-34.
   
   

 

2006

1. Krishnaraj Rajalingam, Manu Sharma, Nicole Paland, Oliver Thieck, Monique Oswald, Nikolaus Machuy and Thomas Rudel. (2006) IAP-IAP complexes required for apoptosis resistance of C.trachomatis infected cells. PloS Pathogens 2(10):e114.
   
   

2. Nicole Paland, Krishnaraj Rajalingam, Nikolaus Machuy, Agnes Szczepek, Wolfgang Wehrl and Thomas Rudel. (2006) NF-kappaB and inhibitor of apoptosis proteins are required for apoptosis resistance of epithelial cells persistently infected with Chlamydophila pneumoniae. Cellular Microbiology 8(10):1643-55.

 

2005

1. Krishnaraj Rajalingam, Christian Wunder, Volker Brinkmann, Yuri Churin, Mirko Hekman, Claudia Sievers, Ulf R. Rapp, Thomas Rudel. (2005) Prohibitin is required for Ras induced Raf-MEK-ERK activation and epithelial cell migration. Nature Cell Biology 7(8):837-43.
   Cover feature (image) for August 2005 issue of NCB What is in a name? (2005) Nature Reviews Molecular Cell Biology 6, 674-675 doi: 10.1038/nrc1731. (Evaluated by faculty of 1000 biology & medicine, highlighted in EMBO encounters)
   
   

2. Krishnaraj Rajalingam and Thomas Rudel. (2005) Ras-Raf signaling needs prohibitin. Cell Cycle 4(11):1503-5.
   
   

3. Machuy N*, Thiede B*, Rajalingam K, Dimmler C, Thieck O, Meyer TF, Rudel T. (2005) A global approach combining proteome analysis and phenotypic screening with RNA interference yields novel apoptosis regulators. Molecular and Cellular Proteomics (1):44-55.

 

2004

1. Machuy N, Rajalingam K, Rudel T. (2004) Caspase mediated cleavage of c-Abl is required during cisplatin induced apoptosis. Cell Death and Differentiation 11(3):290-300.

 

2001

1. Rajalingam K, Al-Younes H, Muller A, Meyer TF, Szczepek AJ, Rudel T. (2001) Epithelial cells infected with Chlamydophila pneumoniae (Chlamydia pneumoniae) are resistant to apoptosis. Infection and Immunity 69 (12):7880-8.

 

2000

1. Krishnamurthy KV, Krishnaraj R, Chozhavendan R, and Christopher, F.S. (2000) The programme of cell death in plants and animals - A comparison. Current Science 79 (9): 1169-1181.