Research Groups

 

 

 

 

 

 


 

 

 

 

 

 

 

 

 

Publications

 

Cover

 

2009

  1. Andreas Fischer, Angela Baljuls, Jörg Reinders, Elena Nekhoroshkova, Claudi Sibilski, Renate Metz, Stefan Albert, Krishnaraj Rajalingam, Mirko Hekman, and Ulf R. Rapp (2009) Regulation of RAF Activity by 14-3-3 Proteins –RAF Kinases Associate Functionally with both Homo- and Heterodimeric forms of 14-3-3 Proteins. Journal of Biological Chemistry 284(5):3183-94.

  2. Krishnaraj Rajalingam and Ivan Dikic (2009). Inhibitors of Apoptosis catch ubiquitin. Biochemical Journal 417(1):e1-3. 2008

  3. Oliver Kepp, Kathleen Gottschalk, Yuri Churin, Krishnaraj Rajalingam, Volker Brinkmann, Nikolaus Machuy, Guido Kroemer, Thomas Rudel. (2009) Bim and Bmf Synergize to Induce Apoptosis in Neisseria Gonorrhoeae Infection. (Accpeted in PloS pathogens)

 

2008

  1. Taner Dogan, Gregory S.Harms, Mirko Hekman, Christiaan Karremann, Tripat kaur Oberoi, Emad S.Alnemri, Ulf R Rapp, Krishnaraj Rajalingam. (2008) X linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility. Nature Cell Biology 10 (12):1447-55.

  2. Krishnaraj Rajalingam*, Manu Sharma*, Christine Wolkewitz, Monique Oswald, Christopher J. Froelich, Thomas Rudel. (2008) Mcl-1 is a key regular of apoptosis resistance in Chlamydia trachomatis infected cells. PloS ONE 3(9):e3102

  3. Anatoly Samoylenko, Nadiya Byts, Krishnaraj Rajalingam, Nico von Ahsen, Ulf R. Rapp, Hannelore Ehrenreich and Anna-Leena Sirén. (2008) Thrombopoietin inhibits nerve growth factor-induced neuronal differentiation and ERK1/2 signalling. Cellular Signalling 20(1):154-62.

 

2007

  1. Krishnaraj Rajalingam, Monique Oswald, Kathleen Gottschalk, Thomas Rudel. (2007) Smac is required for effector caspase activation during apoptosis in human cells. Apoptosis 12(8):1503-10.

  2. Krishnaraj Rajalingam, Ralf Schreck, Ulf R Rapp, Stefan Albert. (2007) Ras oncogene and effectors. Biochimica et Biophysica Acta-Molecular Cell Research 1773(8):1177-95.

  3. Oliver kepp§, Krishnaraj Rajalingam§, Sonja Kimmig, and Thomas Rudel. (§Equal contribution) (2007) Bax and Bak are functionally non redundant during Neisseria gonorrhoea and DNA damage- induced apoptosis. EMBO journal 26(3):825-34.

 

2006

  1. Krishnaraj Rajalingam, Manu Sharma, Nicole Paland, Oliver Thieck, Monique Oswald, Nikolaus Machuy and Thomas Rudel. (2006) IAP-IAP complexes required for apoptosis resistance of C.trachomatis infected cells. PloS Pathogens 2(10):e114.

  2. Nicole Paland, Krishnaraj Rajalingam, Nikolaus Machuy, Agnes Szczepek, Wolfgang Wehrl and Thomas Rudel. (2006) NF-kappaB and inhibitor of apoptosis proteins are required for apoptosis resistance of epithelial cells persistently infected with Chlamydophila pneumoniae. Cellular Microbiology 8(10):1643-55.

 

2005

  1. Krishnaraj Rajalingam, Christian Wunder, Volker Brinkmann, Yuri Churin, Mirko Hekman, Claudia Sievers, Ulf R. Rapp, Thomas Rudel. (2005) Prohibitin is required for Ras induced Raf-MEK-ERK activation and epithelial cell migration. Nature Cell Biology 7(8):837-43.
    Cover feature (image) for August 2005 issue of NCB What is in a name? (2005) Nature Reviews Molecular Cell Biology 6, 674-675 doi: 10.1038/nrc1731. (Evaluated by faculty of 1000 biology & medicine, highlighted in EMBO encounters)

  2. Krishnaraj Rajalingam and Thomas Rudel. (2005) Ras-Raf signaling needs prohibitin. Cell Cycle 4(11):1503-5.

  3. Machuy N*, Thiede B*, Rajalingam K, Dimmler C, Thieck O, Meyer TF, Rudel T. (2005) A global approach combining proteome analysis and phenotypic screening with RNA interference yields novel apoptosis regulators. Molecular and Cellular Proteomics (1):44-55.

 

2004

  1. Machuy N, Rajalingam K, Rudel T. (2004) Caspase mediated cleavage of c-Abl is required during cisplatin induced apoptosis. Cell Death and Differentiation 11(3):290-300.

 

2001

  1. Rajalingam K, Al-Younes H, Muller A, Meyer TF, Szczepek AJ, Rudel T. (2001) Epithelial cells infected with Chlamydophila pneumoniae (Chlamydia pneumoniae) are resistant to apoptosis. Infection and Immunity 69 (12):7880-8.

 

2000

  1. Krishnamurthy KV, Krishnaraj R, Chozhavendan R, and Christopher, F.S. (2000) The programme of cell death in plants and animals - A comparison. Current Science 79 (9): 1169-1181.