Ivan Dikic

Ivan Dikic was born and brought up in Zagreb, Croatia, where he was trained as a medical doctor, he obtained his PhD in molecular biology from the University of Zagreb while working under the supervision of Joseph Schlessinger at New York University Medical Center, USA.
He became a Group Leader at the Ludwig Institute for Cancer Research, Uppsala, Sweden moving to Frankfurt in 2002.
He is currently a Professor and Director of Institute of Biochemistry II at the Goethe University, Frankfurt, Germany and was the Founding Director of the Buchmann Institute for Molecular life Sciences (BMLS) from 2009-2013. He also holds a Guest Professorship at the University of Split, Croatia.
Ivan's scientific interests are focused on how ubiquitin pathways regulate cellular processes, such as receptor-mediated endocytosis, immune responses, DNA repair, proteasomal degradation and more recently on molecular basis of selective autophagy.

Ivan Dikic
Ivan Dikic
IBCII Director
Group leader


Education

1995 – 1997 Postdoctoral Fellow, New York University Medical Center, New York, USA
1991 – 1995 Ph.D. - Molecular Biology University of Zagreb and New York University under supervision of Prof. J. Schlessinger
1986 – 1991 Medical Doctor, University of Zagreb Medical School, Summa cum laude


Positions Held

2009 – Scientific Director, Institute of Biochemistry 2, Goethe University Frankfurt am Main, Germany
2009 – 2013 Founding Director, Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt am Main, Germany
2002 – Professor, School of Medicine University of Split, Croatia
2005 – 2010 Adjunct Investigator, Tumour Biology Program, MedILS, Split, Croatia
2002 – 2008 Professor, Institute of Biochemistry II, Goethe University, Medical School, Frankfurt am Main, Germany
1997 – 2002 Group Leader, Ludwig Institute for Cancer Research, Uppsala, Sweden
1992 – 1997 Research Associate at the New York University, NY, USA
1991 – 1992 Intern, International Institute for Mother and Child Health Care, Zagreb, Croatia

 

Professional Activities

2012 – Vice-Speaker and Member of the Board of Directors of the Cluster of Excellence for Macromolecular Complexes, Frankfurt am Main, Germany
2011 – 2012 Speaker of the Frankfurt Autophagy Network, funded by the Goethe University, Frankfurt am Main, Germany
2010 – 2014 Member of the Organizing team for Frankfurt Cancer Institute (FCI), funded by the German Consortium for Translational Cancer Research
2010 - 2014 Executive Committee Member, European Association for Cancer Research (EACR)
2010 – 2013 Member of the Board of Directors, LOEWE Centrum for Gene and Cell Therapy, Frankfurt am Main, Germany
2009 – Chairman of Scientific Advisory Group, SCILLS (Scottish Institute for Cell Signalling), Dundee, Scotland
2009 – Member of the Board of Directors, Cluster of Excellence Macromolecular Complexes, Frankfurt am Main, Germany
2009 – 2014 ERC Life Science panel member
2009 – 2012 EMBO Publication committee member
2009 – 2012 EMBO Advanced Training Centre committee member
2009 – 2012 Member of the Board of Directors, LOEWE Oncology signalling program, Frankfurt am Main, Germany
2009 – 2012

Landon Foundation - AACR INNOVATOR Award Scientific Review

Committee, Washington

 

Memberships

2013 Croatian Academy of Medical Science, elected member
2010 German National Academy of Sciences Leopoldina
2008 Biochemical Society
2008 World Academy of Art and Science (WAAS)
2004 European Molecular Biology Organization (EMBO)
2003 German Association for Cell Biology (DGZ)
2002 German Society for Biochemistry and Molecular Biology, FEBS and IUBMB
2001 International Union Against Cancer
2001 American Society for Biochemistry and Molecular Biology (ASBMB)
2001 European Life Science Organization (ELSO)
2000 American Association for Cancer Research (AACR)


Awards and Honors

2014 Vallee Foundation Visiting Professorship 2014, Harvard Medical School, Boston, USA
2013 Ernst Jung Prize for Medicine 2013, Jung Foundation for Science and Research, Hamburg, Germany
2013 Gottfried Wilhelm Leibniz Prize of the German Research Foundation, Bonn, Germany
2013 William C. Rose Award 2013, American Association for Molecular Biology and Biochemistry for outstanding achievements, Boston, USA
2010 German Cancer Prize, DKG Berlin, Germany
2010 European Research Council (ERC) Advanced Grant, Brussels, EU
2010 The Order of Duke Branimir for international promotion of Croatia – state honour bestowed by the President of Croatia
2009 Sir Hans Krebs Prize, Medical Faculty Hannover, Hannover, Germany
2008 Award of the International Society of Blood Purification, Brijuni Islands
2008 City of Split Award – Annual Prize for Science, Croatia
2006 AACR Award for Outstanding Achievement in Cancer Research, Washington, USA
2006 Young Cancer Researcher Award, European Association for Cancer Research, Budapest, Hungary
2006 Binder Innovation Prize, German Society for Cell Biology, Braunschweig, Germany
2006 Biomedical Science Prize 2006, Glaxo-Smith-Kline-Foundation, Munich, Germany
2002 Lilla Fernström Award, Lund, Sweden
2000 – 2004 Award of the Strategic Funds for Young Leaders, Sweden
1997 – 2003 Research Award, Boehringer Ingelheim Fonds Germany
1991 D. Perovic Award - Best Medical Graduate (GPA 5,0) at University of Zagreb, Croatia
1991 Rector's Award, University of Zagreb, Croatia
1990 Award for Distinguished Students, University of Zagreb, Croatia

 

       
Honorary Lectures

2014 EMBO Keynote Lecture, Cancercon 2014, Chennai, India
2013 Plenary Lecture, Congress of Nephrology 2013, Berlin, Germany
2013 Keynote Lecture, 18th Congress of the European Hermatology Association (EHA), Stockholm, Sweden
2012 Keynote Lecture, National Congress of Biochemistry and Molecular Biology, Chengdu, China
2012 Keynote Lecture, EMBO Molecular Medicine meeting, Cavtat, Croatia
2011 John Humphrey Lecture, Imperial College London, UK
2011 Keynote Lecture, British Society of Cell Biology, Liverpool, UK
2010 Severo Ochoa Lecture, CBM Madrid, Spain
2009 Keynote Lecture, EMBO meeting on Autophagy, Ascona, Switzerland

 

Board Member

2014 Editorial Board Member, Molecular Cell  
2014 Speaker LOEWE Ub-Net - Ubiquitin signalling from Molecular Mechanisms to Human disease, 2014-2017
2014

Member in Charge, COST Aktion BM1307 “European network to integrate research on intracellular proteolysis pathways in health and disease (PROTEOSTASIS)”

2013 – 2015 Gertrude B. Elion Cancer Research Award – AACR Scientific Review Committee, USA
2013 – Pezcoller Foundation – AACR Award Selection Committee, USA
2012 – Member of the Board of Reviewing Editors, eLife Journal
2012 – Editorial Board Member, Developmental Cell
2012 – 2015 Scientific Advisory Board Member, MRC Phoshphorylation and Ubiquitination Unit, Dundee, Scotland
2011 – Editorial Board Member, Journal of Cell Biology
2011 – 2013 Editorial Board Member, Biological Chemistry
2010 Scientific Advisory Board Member, Ubiquigent, Dundee, Scotland
2010 Scientific Advisory Board Member, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark
2010 – 2012 Advisory Board member, Institute of Enzymology, Hungarian Academy of Sciences, Budapest
2010 – 2014 International Advisory Board member, International Institute of Molecular and Cell Biology, Warsaw, Poland
2009 – BMC Biology Editorial Board Member, BioMed Central, London, UK
2008 – Member of the EMBO/EMBL Symposia Committee
2007 Editorial Board member Biochemical Journal
2007 Advisory Editorial Board member EMBO Journal, EMBO Reports
2006 Associate editor, Cancer Research
2006 – 2010 International Advisory Board member, International Institute of Molecular and Cell Biology, Warsaw, Poland
2006 Scientific Advisory Board member of IFOM, Milan
2005 – 2009 Scientific Advisory Board member of Association for International Cancer Research
2005 Highlights Advisor, Nature Reviews Molecular Cell Biology
2003 – 2008 Editorial Board member, Journal of Biological Chemistry
2002 – 2003 Scientific Advisory Board, Betagenon, Stockholm, Sweden

 

Scientific meetings

2015 Organiser EMBO meeting on Ubiquitin and Ubl modifications, Dubrovnik, Croatia
2014 Co-organiser, Cold Spring Harbour Asia, Protein Modification and Homeostasis, Suzhou, China
2014 Organiser, EMBO Conference: Cellular signalling and Cancer Therapy, Dubrovnik, Croatia
2013
Co-organizer EMBO meeting on Ubiquitin and SUMO, Riva del Garde, Italy
2013
Co-organiser Abcam meeting on Ubiquitin and Autophagy, Amsterdam, Netherlands
2012
Organiser, Keystone Symposium “Ubiquitin Signaling”, Whistler, Canada
2012
Organiser, Mosbacher Colloquium “Chemistry and biology of Signal integration”, Mosbach, Germany
2012
Co-organiser, EMBO Practical Course on Ubiquitin and SUMO, Sardinia, Italy
2011
Organiser of the session “Protein synthesis and degradation”, ASBMB Annual Meeting, Washington, USA
2010
Chair, EMBO Conference: “At the joint edge of cellular microbiology & cell biology" – Krakow, Poland
2010
Co-organiser, EMBO Lecture Course Ubiquitin and DNA Damage response, Rovinj, Croatia
2010
Co-Organiser, EMBO Practical Course on Ubiquitin and SUMO, Split, Croatia
2009
Organiser, FEBS Practical Course on Protein Interaction Modules, Split, Croatia
2008
MedILS Summer School: Hot topics in Protein research, Split, Croatia
2008
Co-chair, ELSO Annual meeting, Nice, France
2008
Chair, EMBO Conference: Molecular medicine and cellular signalling, Dubrovnik, Croatia
2008
Co-chair, EMBO Conference: At the joint edge of cellular microbiology and cell biology, Villars-sur-Ollon, Swiss
2006 – 2008
Organiser, EMBO Practical Course on Ubiquitin and SUMO, Split, Croatia
2004
Organiser, FEBS Lecture Course on Cellular Signalling, Dubrovnik, Croatia
2001
Chair, EMBO Lecture Course on Signalling and Development, Split, Croatia
1998 – 2006
Founder and co-organizer, Dubrovnik conferences on Signaling, Dubrovnik/Cavtat, Croatia
1997 – 2012
Mentor for 10 Ph.D. and 9 M.Sc. students
2003 – 2012
Numerous seminars, practicum for medical students in Goethe
2008
MedILS summer school and practical courses, Split, Croatia
2004 -
EMBO and FEBS summer schools and practical courses
2003 – 2004
Seminar courses and computer-based problem solving practicum in Biochemistry at the Goethe University Medical School, Frankfurt, Germany
2000 – 2001
Graduate course in Cellular Signalling - Karolinska Institute, Hudinge, Sweden
2000
Advanced Course in “Physiology: Cellular and Molecular Aspects”, The Wenner-Gren Institute, Stockholm University, Sweden
2000
Graduate Course in Molecular Biology, Split University, Split, Croatia
1999 – 2000
Graduate Course in Cell Signalling, Uppsala University, Uppsala, Sweden
1995 – 1997
Research Instructor, New York University, Medical School, NY, USA


Mentor for students and education

1997 – 2013 Mentor for 13 Ph.D. and 10 M.Sc. students
2003 – 2012 Numerous seminars, practicum for medical students in Goethe
2008 MedILS summer school and practical courses, Split, Croatia
2004 -    EMBO and FEBS summer schools and practical courses
2003 – 2004 Seminar courses and computer-based problem solving practicum in Biochemistry at the Goethe University Medical School, Frankfurt, Germany
2000 – 2001 Graduate course in Cellular Signalling - Karolinska Institute, Hudinge, Sweden
2000 Advanced Course in “Physiology: Cellular and Molecular Aspects”, The Wenner-Gren Institute, Stockholm University, Sweden
2000 Graduate Course in Molecular Biology, Split University, Split, Croatia
1999 – 2000 Graduate Course in Cell Signalling, Uppsala University, Uppsala, Sweden
1995 – 1997

Research Instructor, New York University, Medical School, NY, USA

 

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