Ivan Dikic

Ivan Dikic was born and brought up in Zagreb, Croatia, where he was trained as a medical doctor, he obtained his PhD in molecular biology from the University of Zagreb while working under the supervision of Joseph Schlessinger at New York University Medical Center, USA.
He became a Group Leader at the Ludwig Institute for Cancer Research, Uppsala, Sweden moving to Frankfurt in 2002.
He is currently a Professor and Director of Institute of Biochemistry II at the Goethe University, Frankfurt, Germany and was the Founding Director of the Buchmann Institute for Molecular life Sciences (BMLS) from 2009-2013. He also holds a Guest Professorship at the University of Split, Croatia.
Ivan's scientific interests are focused on how ubiquitin pathways regulate cellular processes, such as receptor-mediated endocytosis, immune responses, DNA repair, proteasomal degradation and more recently on molecular basis of selective autophagy. Read More...

Ivan Dikic
Ivan Dikic
IBCII Director
Group leader
 

David McEwan

David studied Medical Biochemistry at the University of Glasgow and completed a one-year placement in the protein biochemistry department at GlaxoSmithKline, Harlow, UK.
He graduated in 2003 and started his PhD studies at the Beatson Institute for Cancer Research, Glasgow under the supervision of Prof. Margaret Frame.
This was a collaborative study with Prof. Miles Houslay (University of Glasgow) aimed at investigating the effect of cyclic-AMP on colon cancer survival.
David completed his PhD in October 2007 and started his post-doctoral studies in February 2008 with Prof. Ivan Dikic's lab in Frankfurt, Germany.
David's current research interests are focused on understanding how the process of autophagy is regulated and how specific proteins/organelles are targeted for degradation. Read More...
David McEwan
Postdoctoral fellow

 
 

Sjoerd van Wijk

Sjoerd van Wijk was born in Rotterdam, the Netherlands where he was trained as research technician.
In 2004, he graduated cum laude from Maastricht University, the Netherlands. After that, he finished his PhD in the lab of Prof. Marc Timmers (Department of Physiological Chemistry, University Medical Centre Utrecht, the Netherlands, working on the genome-wide selectivity of E2 and E3 enzymes in the human ubiquitin system, using a combination of high-throughput yeast two-hybrid screens and homology modeling and molecular dynamics analysis.
From that moment, he started as post-doc in the lab of Ivan Dikic, working on systems biology of ubiquitin signaling using a combination of high-accuracy mass-spectrometry and quantitative single molecule microscopy, in healthy and oncogenic conditions. Read More...

Sjoerd van Wijk
Postdoctoral fellow

 
 

Aliaksandr Khaminets

Aliaksandr received his PhD under supervision of Prof. Jonathan C. Howard in the Institute for Genetics in Cologne, Germany, working on mechanisms of innate immunity to the protozoan parasite Toxoplasma gondii.
Soon after that he started postdoctoral training in the Molecular Signalling Group led by Prof. Ivan Dikic.
One of major focuses of research is to advance understanding of selectivity of autophagy process. Read More...
Aliaksandr Khaminets
Postdoctoral fellow

Jaime Lopez-Mosqueda

Jaime was born and raised in Los Angeles, California.  He obtained his Bachelor's degree from the California State University, Northridge.  Jaime then ventured to Northern California where he obtained his Ph.D. from the University of California, San Francisco.  Under the mentorship of Prof. David Toczyski, Jaime's dissertation focused on how DNA replication is regulated during adverse conditions.  He is now an EMBO fellow in the lab of Prof. Ivan Dikic in Frankfurt, Germany. Jaime is currently investigating the role of Wrnip1 and ubiquitin signaling in DNA metabolism. Read More...
Ivan Dikic Jaime Lopez-Mosqueda
Postdoctoral fellow

Veronique Schaeffer

Véronique did her PhD in joint supervision between the University of Basel (Switzerland) and the University of Strasbourg (France) investigating the role of endogenous neurosteroids in the regulation of neurodegenerative processes. Afterwards, Véronique worked in the group of Dr. Goedert (MRC - Laboratory of Molecular Biology, Cambridge, UK) where she has developed and characterized a transgenic mouse model of TDP-43 proteionopathy. She also conducted another project investigating the effect of autophagy stimulation on neurodegeneration in a mouse model of tauopathy. Véronique is now doing a second postdoc in the lab of Prof. Dikic where she intends to investigate further autophagic pathways. Read More...
Veronique Schaeffer
Postdoctoral fellow

Paolo Grumati

Paolo was born in Vittorio Veneto (TV), Italy. He obtained his master degree in Medical Biotechnologies and his PhD in Genetic and Molecular Biology of Development at Padova University, Italy. Under the mentorship of Prof. Bonaldo, Paolo investigated the molecular mechanisms responsible for the muscular dystrophies linked to collagen VI absence. In particular he performed several studies in order to understand the role of autophagy in skeletal muscle homeostasis and disease. In October 2013 he joined Prof. Dikic's lab as post-doc and he is actually involved in a project aimed to better elucidate mechanisms of selective autophagy. Read More...
Paolo Grumati
Postdoctoral fellow

Doris Popovic

Doris Popovic studied molecular biology at the University of Zagreb, Croatia, at the Faculty of Science. She did her Diploma at the Institute Ruder Boskovic, Zagreb, under the guidance of Dr. Renata Novak investigating the role of protein CTCF in epigenetic regulation of IGF2 and H19 gene imprinting.
Upon graduation she joined Prof. Dikic group at MedILS, Split , Croatia, for practical programm where she was involved in project: Ubiquitin like modifiers in autophagy.
Currently she is doing her PhD in Prof. Dikic lab Frankfurt working on regulation of autophagy by endocytic pathways and other vesicular trafficking events. Read More...
Doris Popovic
PhD. Student

Evgenij Fiškin

Evgenij studied Biochemistry at the Free University Berlin and obtained his diploma degree in 2010. For his diploma thesis he joined the lab of Sven Diederichs at the German Cancer Research Center in Heidelberg to investigate the role of long-non coding RNAs (lincRNAs) in the DNA damage response. To finish his diploma work he worked in the group of Lee Zou at the Harvard Medical School in Boston. He is now a BIF PhD fellow in the lab of Ivan Dikic in Frankfurt, studying ubiquitin signaling. Read More...

 

Evgenij Fiškin
PhD. Student

Masuda Sader

 
 

Anja Kirchhof

 
 

 

 

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