Members

 

Ivan Dikic

Ivan Dikic was born and brought up in Zagreb, Croatia, where he was trained as a medical doctor, he obtained his PhD in molecular biology from the University of Zagreb while working under the supervision of Joseph Schlessinger at New York University Medical Center, USA.
He became a Group Leader at the Ludwig Institute for Cancer Research, Uppsala, Sweden moving to Frankfurt in 2002.
He is currently a Professor and Director of Institute of Biochemistry II at the Goethe University, Frankfurt, Germany and was the Founding Director of the Buchmann Institute for Molecular life Sciences (BMLS) from 2009-2013. He also holds a Guest Professorship at the University of Split, Croatia.
Ivan's scientific interests are focused on how ubiquitin pathways regulate cellular processes, such as receptor-mediated endocytosis, immune responses, DNA repair, proteasomal degradation and more recently on molecular basis of selective autophagy. Read More...

Ivan Dikic
Ivan Dikic
IBCII Director
Group leader
 

Florian Bonn

Florian studied biochemistry at the University of Greifswald. After graduating in 2009 he started his PhD studies also in Greifswald at the Institute for Microbiology in the labs of Michael Hecker and Dörte Becher. During his dissertation he investigated the antibiotic stress response of Staphylococcus aureus with gel-free proteomics. In addition, he worked as an LC-MS specialist in the institute and could gather experience with a wide range of mass-spectrometers. Florian completed his PhD work in 2015 and after a short PostDoc in Greifswald he joined Ivan Dikics group in April 2016. As part of the SFB 1177 Florian is responsible for mass-spectrometry and assisting the group in development of new protocols for proteomic experiments. Read More...

Florian Bonn
Postdoctoral fellow

 
 

Jaime Lopez-Mosqueda

Jaime was born and raised in Los Angeles, California.  He obtained his Bachelor's degree from the California State University, Northridge.  Jaime then ventured to Northern California where he obtained his Ph.D. from the University of California, San Francisco.  Under the mentorship of Prof. David Toczyski, Jaime's dissertation focused on how DNA replication is regulated during adverse conditions.  He is now an EMBO fellow in the lab of Prof. Ivan Dikic in Frankfurt, Germany. Jaime is currently investigating the role of Wrnip1 and ubiquitin signaling in DNA metabolism. Read More...

Ivan Dikic Jaime Lopez-Mosqueda
Postdoctoral fellow

Hadir Marei

Hadir was born in Cairo, Egypt. She obtained her Bachelor’s degree in Biology with a minor in Chemistry at the American University in Cairo. During her Bachelor’s degree, she also participated in an Erasmus exchange program, where she conducted her third year at the University of St. Andrews, Scotland. Following her Bachelor’s, Hadir was awarded a Cancer Research UK studentship to conduct a four-year PhD program at the Cancer Research UK Manchester Institute (CRUKMI) in the Cell Signalling group headed by Dr. Angeliki Malliri. During her PhD, Hadir was focused on dissecting the molecular mechanisms involved in dictating the biological outcomes mediated by the small GTPase Rac1, a key regulator of cytoskeletal rearrangements and cell migration. Stemming from her interest in small GTPases, Hadir joined the Dikic group as a postdoctoral fellow, where she is currently investigating the role of regulators of Rab GTPases in modulating autophagy. Additionally, she is also exploring the interplay between cytoskeletal regulators and the trafficking machinery, under normal and pathological conditions. Given her scientific background, Hadir is also interested in identifying novel proteins that modulate the cytoskeleton, particularly following bacterial infection. Read More...

Hadir Marei
Postdoctoral fellow

Veronique Schaeffer

Véronique did her PhD in joint supervision between the University of Basel (Switzerland) and the University of Strasbourg (France) investigating the role of endogenous neurosteroids in the regulation of neurodegenerative processes. Afterwards, Véronique worked in the group of Dr. Goedert (MRC - Laboratory of Molecular Biology, Cambridge, UK) where she has developed and characterized a transgenic mouse model of TDP-43 proteionopathy. She also conducted another project investigating the effect of autophagy stimulation on neurodegeneration in a mouse model of tauopathy. Véronique is now doing a second postdoc in the lab of Prof. Dikic where she intends to investigate further autophagic pathways. Read More...

Veronique Schaeffer
Postdoctoral fellow

Alexandra Stolz

Alexandra received her PhD under supervision of Prof. Dieter H. Wolf in the Institute of Biochemistry in Stuttgart, Germany, working on the identification and characterization of new players of endoplasmic reticulum associated protein degradation (ERAD).
She started her postdoctoral training in the Protein Engineering Group of Dr. Andreas Ernst in September 2013. She is focused on the development of peptide-based sensors for key players of the Ubiquitin and autophagy system. Read More...

 

Alexandra Stolz
Postdoctoral fellow

Paolo Grumati

Paolo was born in Vittorio Veneto (TV), Italy. He obtained his master degree in Medical Biotechnologies and his PhD in Genetic and Molecular Biology of Development at Padova University, Italy. Under the mentorship of Prof. Bonaldo, Paolo investigated the molecular mechanisms responsible for the muscular dystrophies linked to collagen VI absence. In particular he performed several studies in order to understand the role of autophagy in skeletal muscle homeostasis and disease. In October 2013 he joined Prof. Dikic's lab as post-doc and he is actually involved in a project aimed to better elucidate mechanisms of selective autophagy. Read More...

Paolo Grumati
Postdoctoral fellow

Lina Herhaus

After high school Lina obtained her first lab work experience in Mexico at the Research centre ECOSUR in San Cristóbal de las Casas. She then decided to study Applied Biology at Hochschule Bonn-Rhein-Sieg (Germany) and Molecular Biology at the University of Dundee (UK) where she obtained a double degree with Honours. Lina performed her PhD studies at the MRC Protein Phosphorylation and Ubiquitylation Unit in Dundee under the supervision of Dr. Gopal Sapkota. Her dissertation focused on how deubiquitylating enzymes regulate the TGF-beta and BMP signaling pathways. Lina is now an EMBO fellow in the lab of Prof. Ivan Dikic in Frankfurt (Germany), where she will investigate the role of ubiquitylation on tumor-stroma crosstalk.
Read more...

 


Lina Herhaus

Postdoctoral fellow

Marta Seczynska

Marta Seczynska studied biotechnology at the Jagiellonian University in Krakow, Poland, where she obtained her master’s degree in 2015. For the diploma thesis, she joined Department of Medical Biotechnology where she was investigating the biology of muscle progenitor cells and their role in muscle tumorigenesis. Marta is now PhD student in the lab of Prof. Ivan Dikic, where she is focused on the mechanisms and regulation of autophagy.
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Marta SeczynskaMarta Seczynska
PhD. Student

Evgenij Fiškin

Evgenij studied Biochemistry at the Free University Berlin and obtained his diploma degree in 2010. For his diploma thesis he joined the lab of Sven Diederichs at the German Cancer Research Center in Heidelberg to investigate the role of long-non coding RNAs (lincRNAs) in the DNA damage response. To finish his diploma work he worked in the group of Lee Zou at the Harvard Medical School in Boston. He is now a BIF PhD fellow in the lab of Ivan Dikic in Frankfurt, studying ubiquitin signaling. Read More...

 

Evgenij Fiškin
PhD. Student

Stefan Prgomet

Stefan studied medicine at the University of Zagreb Medical School where he obtained his MD in 2013 and his medical licence in 2014. He has been working at the Laboratory for mineralized tissues under supervision of prof.dr.sc. Slobodan Vukicevic and prof.dr.sc. Lovorka Grgurevic investigating the role of BMP signaling pathways in bone repair and liver cirrhosis. He has been working at the Department of Neurosurgery in the Clinical Hospital Dubrava where he also joined the project RONNA (RObotic Neuro-NAvigation) under guidance of prof.dr.sc. Darko Chudy. Stefan is currently investigating Spartan, a newly identified molecule connected to liver cancer. Read More...

 

Stefan Prgomet
PhD. Student

Masuda Sader

 
 

Anja Kirchhof

 
 

 

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