Stefan Müller was born in Augsburg, Germany. He studied pharmacy at Ludwig-Maximilians-University Munich and obtained his diploma and approbation in 1991.
He subsequently worked as a Ph.D. student and research assistant in the Institute of Physiological Chemistry at Hamburg University under the supervision of Prof. Seitz and graduated in 1995.
With a Marie-Curie post-doctoral fellowship from the EU he joined the laboratory of Dr. Anne Dejean at Pasteur Institute, Paris. Here he discovered the post-translational modification of PML by the ubiquitin-like SUMO modifier.
He continued investigating the SUMO system and in 2001 became a group leader at Max Planck Institute of Biochemistry in Martinsried in the Department of Molecular Cell Biology.
In 2010 he was appointed W2 professor in biochemistry at IBCII.
Professor (W2)
Goethe University, Medical School, Frankfurt am Main, Germany,
Institute of Biochemistry II
2001 - 2010
Group Leader
Max-Planck Institute of Biochemistry, Martinsried, Germany
Department of Molecular Cell Biology
1995 - 2000
Post-Doctoral Fellow (Marie Curie Fellowship)
Pasteur Institute, Paris, France
Unité de Recombinaison et Expression Génétique
Research group: Dr. Anne Dejean
1991 - 1995
Ph.D. Student and Research Assistant
University of Hamburg, Germany
Institute of Physiological Chemistry
Department of Biochemical Endocrinology
Head: Prof. Dr. H. J. Seitz
Education
March 1995
Doctorate (Promotion) in Natural Sciences, University of Hamburg, Germany
Supervisor: Prof. Dr. H. J. Seitz
January 1991
Diploma and Approbation in Pharmacy
1986 – 1991
Studies of Pharmacy, Ludwig-Maximilians-University, Munich, Germany
Nithya Raman
Nithya Raman was born in Bangalore, India. She obtained her Bachelor's degree in the field of Biotechnology from Visvesvaraya Technological University, Karnataka in 2007. Following this she did her Master's in Biotechnology and Biochemical Engineering at the Indian Institute of Technology (Kharagpur, India). During her Master's she was awarded the DAAD Sandwich Model scholarship to pursue her project for nine months at RWTH Aachen, Germany in 2008. Subsequently, she joined the lab of Stefan Müller for PhD under the IMPRS-LS program at Max Planck Institute of Biochemistry, Martinsried in 2009. She now works at the Institute of Biochemistry II, Goethe University, Frankfurt am Main, in the group of Prof. Stefan Müller where she is studying the regulatory functions of SUMO in ribosome biogenesis and the functional characterization of the phosphoSIM module of PIAS1
PhD Student at the Institute of Biochemistry II, J.W. Goethe University Medical Center in the SUMO signaling group of Prof. Stefan Müller
2009-2010
PhD student at the Max Planck Institute of Biochemistry, Department of Molecular Cell Biology, in the group of Stefan Müller
2008-2009
Master's thesis at RWTH Aachen, Germany
2007-2009
Master of Technology (M.Tech) in Biotechnology and Biochemical engineering from IIT, Kharagpur
2003-2007
Bachelor of Engineering (B.E) in Biotechnology from R.V. College of Engineering, Bangalore (affiliated to Visvesvaraya Technological University)
Arnab Nayak
After finishing M.Sc. from Banaras Hindu University (India), Arnab received a CSIR (Council of Scientific and Industrial Research)- Junior Research Fellowship and worked for a short-term at National Centre for Cell Science, Pune, India. With a scholarship from the Graduate school in Immunomodulation in Germany, Arnab worked in the lab of Prof. Edgar Serfling, University of Wuerzburg. His PhD project was focused on the regulation of transcription factor (NFATc1) function by sumoylation and its consequences in T cell differentiation. Then he moved to Cambridge University, UK for a postdoctoral research. His study in Cambridge was to understand how TAO1 kinase protein controls mitosis.
At present Arnab is working with Prof. Stefan Müller group. The main objective of his present research is to understand the mechanisms by which reverse sumoylation signaling regulates transcription.
Postdoctoral fellow, Goethe University, Medical School, Frankfurt am Main, Germany, Institute of Biochemistry II
2009 - 2011
Postodoctoral Research Associate, Department of Genetics, Cambridge university, UK
2004 - 2008
PhD in Biological Sciences from Würzburg University, Germany. Grade: Sehr Gut
2002-2003
Junior Research Fellow, National Center for Cell Science (NCCS, Pune), India.
1999-2001
Master of Science (M.Sc.), in Zoology (specialization in Molecular Genetics) from Banaras Hindu University (BHU) India. Grade: 1st class.
1996-1999
Bachelor of Science (B.Sc.) in Zoology (Hons), Chemistry and Botany from Burdwan University WB, India. Grade: 1st class
Selected publications
Arnab Nayak, Judith Glöckner-Pagel, Mathias Buttmann, Tobias Bopp, Edgar Serfling, and Friederike Berberich-Siebelt. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and repression of IL-2 by HDAC. J Biol Chem. 2009 Apr 17;284(16):10935-46.
Doris Schmidt, Arnab Nayak, Anneliese Schimpl, Ingolf Berberich and Friederike Berberich-Siebelt. Blimp-1∆exon7: A naturally occurring Blimp-1 deletion mutant with auto-regulatory potential. Exp. Cell Res. 2008 Dec 10; 314(20):3614-27.
Arnab Nayak, Roshan L Shrestha and Viji M Draviam. Sumoylation – an emerging player in protein modification and cell function, Journal of Scientific Research2010, (54) 63-72.
Marc Sawatzki studied Biology at the Zentrum für Human- und Molekularbiologie (ZHMB) in Saarbrücken and Homburg. In his diploma thesis he investigated Sumoylation of several Saccharomyces cerevisiae proteins under the supervison of Prof. Schlenstedt. In 2011 he joined Prof. Müller´s group at the IBCII in Frankfurt as a PhD-student. His project concentrates on the characterization of the nucleolar key regulator nucleophosmin (NPM1) and the leukemia-associated mutant NPM1c.
AGAP, a Novel Binding Partner of Nitric Oxide-sensitive Guanylyl Cyclase (The Journal of Biological Chemistry Vol. 279, No. 47, Issue of November 19, pp 49346-49354, 2004) Sabine Meurer, Sylke Pioch, Kristina Wagner, Werner Müller-Esterl, and Steffen Gross
