Dr. Mohit Misra
Mohit completed his master's degree in Biotechnology at JMI University, New Delhi in addition to a Postgraduate Diploma in Bioinformatics affiliated to NIELIT, Kolkata. He worked as a Junior Research Fellow at the International Center for Genetic Engineering and Biotechnology in the Recombinant Gene Products lab led by Dr. Navin Khanna. He moved to Germany to the Rudolf Virchow Center for Experimental Biomedicine, University of Würzburg in the lab of Prof. Hermann Schindelin to obtain his PhD where he worked at the apex of the ubiquitylation pathway trying to decipher the structure-function relationship of the ubiquitin-activating enzyme (Uba1) and its interactions with the E2 enzymes. He also determined the structural basis of the variable potency of E1 inhibitors towards Uba1 which hold promise for cancer therapy. After a brief postdoc in Würzburg, Mohit continues to pursue his fascination for ubiquitin and has joined the Dikic lab to explore the novel chemistry of serine ubiquitylation both structurally and biochemically.